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- Purpose:To detect the effect and mechanism in hepatocarcinogenesis induced by HBV and aflatoxin B 1 (AFB 1) in tree shrews, two animal experiments had been done. 目的 :探讨乙肝病毒 (HBV)和黄曲霉毒素B1(AFB1)在肝癌形成中的作用及机理。
- INT ERVENTION:For the trial group,animals were fed with AFB 1 (aflatoxin B 1 )till the 105th week,and then with normal animal food till the 150th week when experiment ended. 干预:实验组给予AFB1(黄曲霉毒素B1)105周,然后继续喂正常饲料至150周。
- Objective To study the glutathione S tranterase M1(GSTM1) genotype in patients with hepatocellular carcinoma (HCC) with aflatoxin B 1(AFB 1) in a high risk region in Guangxi. 目的 研究广西黄曲霉毒素 (AFB1)高危区肝细胞癌 (HCC)患者谷胱甘肽转移酶 (GST)M1的基因型。
- AIM To study the effect of antihepatitis drug, dimethyl diphenyl bicarboxylate (DDB) on the metabolism and hepatotoxicity of aflatoxin B 1 (AFB 1) in rats. 目的 研究抗肝炎药联苯双酯对大鼠黄曲霉毒素B1代谢和肝毒性的影响。
- Keywords GST P Li 2CO 3 Aflatoxin B 1 Preneoplastic lesion; 关键词胎盘型谷胱甘肽硫转移酶;碳酸锂;黄曲霉毒素B_1;癌前病变;
- The adsorption of aflatoxin B 1 by modified montm orillonite was not affected by lysine at concentration of 2.0 mg/mL and 4.0 mg/m L,pH range from 2.0 to 8.0 and temperature changes. 赖氨酸含量为 2 .;0mg/mL和 4
- Using aflatoxin B 1(AFB 1) as a model carcinogen,we have studied the effect of food restriction (FR) on the metabolic activation of AFB 1 in male Fischer 344 rats and B6C3F 1 mice. 本实验用黄曲霉毒素B1(AflatoxinB1,AFB1)作为致癌物代表,研究限量饮食(Foodrestriction,FR)对雄性F344大鼠和B6C3F1小鼠代谢活化AFB1的影响。
- Objective To investigate the effects of 2(3) tert 4 hydroxyanisole (BHA) on protection against synergistic hepatocarcinogenesis of aflatoxin B 1 (AFB 1) and hepatitis B virus (HBV) expression in HBV large envelope transgenic mice. 目的研究抗氧化剂2,3?叔丁基?4?羟基茴香醚(BHA)对黄曲霉毒素(AFB1)染毒的乙型肝炎病毒(HBV)转基因小鼠肝肿瘤发生的防护作用。
- Objective To observe the histopathological change and the expression of glutathione S transferase of placental type(GST P) in Aflatoxin B 1(AFB 1) induced rat hepatic putative preneoplastic lesions alleviated by lithium carbonate(Li 2CO 3). 目的观察碳酸锂 (Li2 CO3)对抗黄曲霉毒素B1(AFB1)诱发的大鼠肝癌前病变的组织形态学变化及胎盘型谷胱甘肽硫转移酶 (GST P)的表达。 方法采用肝癌发生的动物模型。
- To be showed that DR significantly inhibited aflatoxin B 1(AFB 1) DNA major adduct and 2 acetylaminofluorene (2 AAF) DNA major adduct (AF ?C? 8 dG) formation as well as carcinogen induced strand breaks. 限量饮食减少小鼠肝中黄曲霉毒素B1(AFB1)?和2?乙基氨基芴(2?AAF)?DNA加合物(AF?C8?dG)的生成,同时也减少致癌物导致的DNA链断裂;
- Keywords Carcinoma;hepatocellular;Glutathione S transferase M1;Aflatoxin B 1;GSTM1 genotype; 癌;肝细胞;谷胱甘肽转移酶M1;黄曲霉毒素;GSTM1基因型;
- 4 strains of Aspergillus flavas were found, 2 of them were toxigenic. Aflatoxin B 1 production were 6? 7 ng/g respectively and they didn?t produce AFB 2? 在检出的4株黄曲霉菌株中2株为产毒株 ,黄曲霉毒素B1 产量分别为6、7ng/g,均不产生黄曲霉毒素B2、G1、G2。
- Aflatoxin B 1 黄曲酶毒素B1
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- Keywords aflatoxin germ method of deracinating toxin food; 黄曲霉菌;去毒方法;食品;
- Keywords Aflatoxin;highly toxic substances;carcinogenic;detection; 黄曲霉毒素;剧毒物质;致癌性;检测;
- Keywords aflatoxin M1;monoclonal antibody;tumour cell; 黄曲霉毒素M1;单克隆抗体;瘤细胞;
- OBJECTIVE:To find the conditions of the Chinese materia media polluted by aflatoixin B 1(AFB 1). 目的 :了解中药污染黄曲霉毒素B1(AFB1)情况。
- Keywords aflatoxin;immunoaffinity column;fluorometer mensuration;soy sauce; 黄曲霉毒素;免疫亲和层析;荧光光度法;酱油;
- The nutrition components of Atractomorpha sinensis Bolivar were analysed,which include protein,amino acid,total sugar,fat,fatty acid,vitamin B 1,B 2,C and E. 本文分析了短额负蝗AtractomorphasinensisBolivar的营养成分 ,包括蛋白质、氨基酸、总糖、粗脂肪、脂肪酸及维生素B1,B2 ,C和E。